Nytol One-A-Night – 20 Tablets


  • Easy to swallow tablets
  • Clinically proven night time sleep aid
  • Relief from temporary sleeping difficulties
  • Helps with relaxation

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  • Genuine Medicine Approved by MHRA
  • Regulated NHS & Online Pharmacy
  • Free Delivery for orders above £30
  • Free Private Prescription included


What is Nytol and how does it work?

Nytol is an over-the-counter tablet that aids sleep and treats insomnia. This medication contains diphenhydramine, an antihistamine commonly used to treat allergies. As diphenhydramine is known to cause drowsiness, it is also often used to help people sleep.

Does Nytol work?

Nytol is clinically proven to help individual experiencing sleeping difficulties. It helps to induce sleep and deeper sleep, and increase sleep duration, leaving you feeling refreshed in the morning.

How do I take Nytol?

One tablet should be taken orally with water, around 20 minutes before going to bed.

How long does Nytol take to work?

For each use, Nytol should kick in around 20 minutes after taking the tablet. Nytol should be taken for a maximum of 2 weeks at a time. If your sleep has not improved in this time, then speak with your pharmacist or doctor.

Is Nytol suitable for me?

Nytol is suitable for most people except those who are pregnant, feeding, or children under 16. Consult your doctor before use if you suffer from COPD, epilepsy (or any seizure activity), gut issues (e.g. ulcers), or liver or kidney disease.

Side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Common side effects of Nytol relate to its drowsiness mode of action and include dizziness, unsteadiness, and difficultly concentrating.

More information

For more information, please refer to the product patient information leaflet.